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Image Search Results
Journal: The Journal of Biological Chemistry
Article Title: Fasting induces hepatic lipid accumulation by stimulating peroxisomal dicarboxylic acid oxidation
doi: 10.1016/j.jbc.2021.100622
Figure Lengend Snippet: A , body weight loss in the fasting rats. B , liver free fatty acids were remarkably increased in the fasting rats. C , liver TAG increased significantly in the fasting rats. D , gene expression of fatty acids ω-oxidation and peroxisomal β-oxidation in liver were upregulated by fasting. E , liver DC-CoA was significantly higher in fasting rats. F , liver peroxisomal β-oxidation was robustly induced in fasting rats. ABCD1, peroxisomal ATP-binding cassette transporter D; ACOX1, acyl-CoA oxidase-1; ACS, acyl-CoA synthetase; L-BP, L-bifunctional protein; LCADH, long-chain alcohol dehydrogenase; Thiolase, peroxisomal 3-oxoacyl-CoA thiolase. Mean ± SEM, n = 8, ∗ p < 0.05 by t -test between paired conditions.
Article Snippet: Plasma FFA concentration was determined using a colorimetric kit based on
Techniques: Expressing, Binding Assay
Journal: The Journal of Biological Chemistry
Article Title: Fasting induces hepatic lipid accumulation by stimulating peroxisomal dicarboxylic acid oxidation
doi: 10.1016/j.jbc.2021.100622
Figure Lengend Snippet: A , kinetic parameters of key enzymes involved in peroxisomal and mitochondrial β-oxidation with C 12 -CoA and DC 12 -CoA as substrates. Mean ± SEM, n = 3. B , liver peroxisomal and mitochondrial β-oxidation activities with C 12 -CoA and DC 12 -CoA as a substrate respectively. ACOX1, acyl-CoA oxidase-1; CPT1, carnitine palmitoyltransferase-1; LCAD, long-chain acyl-CoA dehydrogenase; MCAD, medium-chain acyl-CoA dehydrogenase; SCAD, short-chain acyl-CoA dehydrogenase. Mean ± SEM, n = 6, ∗ p < 0.05 by t -test between paired conditions.
Article Snippet: Plasma FFA concentration was determined using a colorimetric kit based on
Techniques: